Familial Mediterranean fever seems to be not uncommon in Greece

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Familial Mediterranean fever associated pyrin mutations in Greece.

OBJECTIVE To search for pyrin mutations associated with familial Mediterranean fever (FMF) in Greece. PATIENTS AND METHODS 62 patients fulfilling the Tel Hashomer diagnostic criteria for definite (33) or probable (29) FMF diagnosis were studied. Eight point mutations of pyrin gene were tested by standard methods. Of the 62 patients tested, 48 were Greek, four were Jewish, seven were Armenian,...

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Familial Mediterranean Fever

Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by MEditerranean FeVer gene (MEFV) mutations. In Japan, patients with FMF have been previously reported, including a mild or incomplete form. Several factors are presumed to contribute to the variable penetrance and to the phenotypic variability of FMF. We conducted the current study to investigate the correlation of varia...

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ژورنال

عنوان ژورنال: European Journal of Human Genetics

سال: 2003

ISSN: 1018-4813,1476-5438

DOI: 10.1038/sj.ejhg.5201096